/;/metadata pX7K6l/5WZ3/ALHt/wDSSSlfsrqX/lZnf+x7f/SSSlfsrqX/AJWZ3/se3/0kkp6DoWLkU9Mtqux7 Clinical development success rates for investigational drugs @article{Hay2014ClinicalDS, title={Clinical development success rates for investigational drugs}, author={M. Hay and D. Thomas and John L Craighead and Celia Economides and J. Rosenthal}, journal={Nature Biotechnology}, year={2014}, volume={32}, pages={40-51} } Do companies in the pharmaceutical supply chain earn excess returns? tblMJsJjNeLLI2s4LQPahLZQeXfl5we6L+p8njHbH/nxNoJY/a8//T9T/wDYZv8A6USoKV9rz/8A qIJY7sf9/pf+Zf8A+QSUrdj/AL/S/wDMv/8AIJKVux/3+l/5l/8A5BJSt2P+/wBL/wAy/wD8gkpW xmp.iid:C0C6722033206811822A842196471FA9 2013-12-17T16:00:46-05:00 Data from five benchmarking studies have shown, with the only significant agreement between studies, how large molecules have had a higher probability of success than small molecules. v/C9X/UNSUx6vlX4eC/Ixn0V2NLQHZJLa9SBqWkJKef/AOcfWf8AuV0f/tx//k0lK/5x9Z/7ldH/ Adobe InDesign 7.0 ALHM/wDIJKV6Nv8A3FyP/Y5n/kElK9G3/uLkf+xzP/IJKV6Nv/cXI/8AY5n/AJBJSvRt/wC4uR/7 xmp.iid:51262CAA2A206811822A85D342A5A7E1 saved g7RsftCv0x+d9D3O+aSndSUpJTX6f/yfjf8AE1/9SElIOt0vyOnWVV1W3OJbDKHip5hw4eUlPM/s pNJSt+H/ANyek/8AsM//ANJpKd/6pmk2ZPpW4dujJ+yVOrI1d9Lc1spKejSUpJTX6f8A8n43/E1/ xmp.iid:2F51A3B2182068118C14889A593A31D7 2013-12-23T13:18:16-05:00 2013-12-18T16:39:22-05:00 7zWbg7ZocYbrf7A01SU8n6mf/pOv/wDbA/8AJpKV6mf/AKTr/wD2wP8AyaSlxZmyN7uvub3b6ESP QiMkFVLBYjM0coLRQwclklPw4fFjczUWorKDJkSTVGRFwqN0NhfSVeJl8rOEw9N14/NGJ5SkhbSV Adobe InDesign 7.0 Adobe InDesign 7.0 Dn7/ALHfXf6cb/TcHRMxMfBJTYSUpJTldL6p0xvTMNrsugOFFQINrAQQxv8AKSUnt6j0W9hruycW Adobe InDesign 7.0 xmp.iid:7CEDCD530E2068118A6DA93610A8227C xmp.iid:F465480D18206811822A9E6D19E15393 saved Adobe PDF Library 9.9 xmp.iid:663C01C83B2068118C14F29C53A9B659 pW3H/c6X/n3/APk0lK24/wC50v8Az7//ACaSlbcf9zpf+ff/AOTSUrbj/udL/wA+/wD8mkpW3H/c /;/metadata xmp.iid:D6DA1274072068118C14A54A67B83CCD tlX2qt2xobufq4wIkn1NSkpW79L6v2qv6O3b+bzMx6nKSlWv9Wt9X2qtu9pbuZo4SIlp9TQpKauL ZeLys4TD03Xj80aUpIW0lcTU5PSltcXV5fVWZnaGlqa2xtbm9ic3R1dnd4eXp7fH1+f3/9oADAMB �[~3��J�D��炂s�r�-x�9�=��Rᴃh���\_M��o*����}F]�������|��KD�w��0�O��� However, the success rate varies wildly depending on the therapeutic area. 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